Chemical reagents are substances with many varieties, frequent consumption and great danger in the laboratory. Such as flammable and explosive chemical reagents, highly toxic chemical reagents, strong corrosiveness, strong oxidizing and other chemical reagents, they should be stored in a special dangerous reagent cabinet after receiving; pay special attention when using them, and take some targeted measures Safety precautions to avoid harm to laboratory personnel and laboratory equipment caused by improper use. Let's talk about the management of chemical reagents in terms of the purchase, storage, storage and safe use of laboratory chemical reagent cabinets.
Acceptance of reagents
There are generally two types of reagent acceptance:
One is compliance acceptance, whether the purchased reagents are in line with the plan. For example, petroleum ether has a boiling range of 30-60°C and 60-90°C.
One is technical verification. The important ones that have an impact on the experiment need to be technically verified, such as nitrogen used for chromatography. If the purity is not enough, it may affect the progress of the experiment, so technical verification is required, or the trial is unqualified.
In the testing process, the quality assurance of reagents for testing results cannot be ignored, so reagent management is very important. Attached is the reagent cabinet management method, hoping to help everyone.
Laboratory reagent management
1. Procurement of reagents
The reagent administrator fills in the purchase application according to the needs of the inspection items, workload and work progress. After the review by the technical person in charge, the laboratory director (or other relevant persons, the laboratory itself determines according to the situation) approves it and then submits it to the purchasing department for purchase and purchase. Purchasing from qualified suppliers in the Qualified Supplier List.
Note: 1. Reagent name, specification and model (500mL/bottle, 4 mL/bottle, etc.), reagent grade (chromatographic pure, excellent grade pure, analytical pure, etc.), quantity, etc. should be included in the purchase application 2. "Qualified Suppliers" The list needs to be reviewed regularly, and unqualified suppliers will be removed in time.
2. Acceptance of reagents After the reagents arrive, the technical person in charge is responsible for organizing the testing room personnel to check the information on the labels, certificates or other supporting documents of the reagent cabinet according to its nature and test type, evaluate the availability, and check whether the reagents meet the corresponding requirements. Whether the requirements of standards and specifications can meet the needs of testing work. The specific acceptance method is based on the "Reagent Acceptance Method" formulated by each laboratory, and the acceptance record is filled in. Note: 1. The laboratory needs to prepare specific reagent acceptance method work instructions. 2. The acceptance record must contain the technical acceptance data of the reagent, such as: the measured boiling range of petroleum ether, blank acceptance, etc. to judge whether the use of the reagent in the test will affect the results.
3. Storage of reagents After the reagents have passed the acceptance inspection, the reagents will be managed by the reagent administrator, and the "Reagent Ledger" will be filled in. The reagent administrator configures the corresponding safety cabinet for storage according to the characteristics of the reagent (considering the toxicity of the reagent, stability to heat, air and light, etc.). Reagent managers monitor the storage environment in accordance with the "Facility and Environmental Management Procedures" to ensure that the culture medium and reagents do not deteriorate, do not damage, and do not degrade performance. Note: 1. The main contents of the reagent ledger include: reagent name, specification and model, production batch number, validity period, manufacturer, inbound quantity, outbound quantity, inventory, etc. 2. Labels are attached to laboratory function cabinets: reagent cabinets, flammable cabinets, acid and alkali resistant cabinets, highly toxic cabinets, etc.
4. Use of reagents When using newly opened reagents, the testing personnel should check their quality. Any reagents with obvious changes in physical properties, precipitation, discoloration, etc. shall not be used. The testing personnel shall use or prepare the reagents in strict accordance with the requirements of the testing methods. When preparing the reagents, fill in the "Reagent Preparation Record" in time. The reagent preparation personnel must sign, and fill in the "Reagent Logo" and affix it to the container containing the reagents. Quality supervisors supervise and inspect the use of the reagents to ensure that the testing personnel use the reagents correctly.
5. Disposal of used reagents After used reagents, strictly follow the "Laboratory Waste Management Regulations" to ensure the safety of discarded reagents and not pollute the environment.